Isaac Reina started his career as an architect student in Barcelona before turning his eye to fashion.  Upon graduating he worked with Italian designer, Antonio Miro.  

He eventually joined Hermes as a men's designer and in 2006 created the Isaac Reina leather bag brand.  The leather used in his design come from the best French and Italian tanneries.  He has also collaborated with fashion icons and  houses Martin Margiela and Balenciaga.